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Posts Tagged ‘triggered’


One disease, two mechanisms: genetic root to early-onset prostate cancer identified

While prostate cancer is the most common cancer in elderly Western men it also, but more rarely, strikes patients aged between 35 and 50. Scientists have discovered that such early-onset prostate cancers are triggered by a different mechanism from that which causes the disease at a later age. Their findings might have important consequences for the diagnosis and treatment of prostate cancer in younger patients.

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Epigenetic analysis of stomach cancer finds new disease subtypes

Researchers have identified numerous new subtypes of gastric cancer that are triggered by environmental factors.

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Learning to overcome fear is difficult for teens

A new study shows that adolescents’ reactions to threat remain high even when the danger is no longer present. According to researchers, once a teenager’s brain is triggered by a threat, the ability to suppress an emotional response to the threat is diminished which may explain the peak in anxiety and stress-related disorders during this developmental period.

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Cells Changing Identity May Trigger Deadly Liver Cancer

A rare type of cancer thought to derive from cells in the bile ducts of the liver may actually develop when one type of liver cell morphs into a totally different type, a process scientists used to consider all but impossible. UCSF researchers triggered this kind of cellular transformation – and caused tumors to form in mice – by activating just two genes…

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Most commonly mutated gene in cancer may have a role in stroke

The gene p53 is the most commonly mutated gene in cancer. p53 is dubbed the “guardian of the genome” because it blocks cells with damaged DNA from propagating and eventually becoming cancerous. However, new research uncovers a novel role for p53 beyond cancer in the development of ischemic stroke. The research team identified an unexpected critical function of p53 in activating necrosis, an irreversible form of tissue death, triggered during oxidative stress and ischemia.

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News From The Journal Of Clinical Investigation: June 11, 2012

ALLERGY AND ASTHMA Evidence for a new therapeutic target for inflammatory skin diseases Many chronic inflammatory diseases, including atopic dermatitis and asthma, are initially triggered by an allergic reaction. However, the mechanism through which an allergic reaction becomes a chronic condition remains poorly understood…

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Cancer Related to Risk of Heart Attack and Suicide

The diagnosis of cancer often leads to agonizing distress for most people. A new study in the April 5, 2012 issue of The New England Journal of Medicine shows that a surprising number of cancer patients die not of cancer, but of a heart attack or suicide triggered by the diagnosis.

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Molecule’s role in cancer suggests new combination therapy

Researchers have found that a molecule found at elevated levels in cancer cells seems to protect them from the “cell-suicide” that is usually triggered by chemotherapy or radiation.

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Sanford-Burhham scientists develop new model of childhood brain cancer

Sanford-Burnham scientists have now developed a new mouse model for studying medulloblastoma. The animal model mimics the deadliest of four subtypes of the human disease, a tumor that is triggered by elevated levels of a gene known as Myc. The study, published February 13 in the journal Cancer Cell, also suggests a potential strategy for inhibiting the growth of this tumor type.

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Jennifer Saunders: My breast cancer drug torment

Jennifer Saunders has revealed that her battle with breast cancer ‘pushed’ her into menopause – and likened it to ‘jumping off a cliff’. The 53-year-old comedy actress said her menopause was triggered by a drug given to women after surgery for the cancer to cut the risk of it coming back.

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