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Discarded immune cells induce the relocation of stem cells

By on Saturday, May 25th, 2013 | No Comments

The study reveals a surprising coordination between two fundamental body systems, the immune and the hematopoietic. The study has implications for the understanding of metastasis, because malignant stem cells involved in tumor formation could take advantage of this mechanism.

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Keeping stem cells strong: RNA molecule protects stem cells during inflammation

By on Wednesday, May 22nd, 2013 | No Comments

A team of researchers led by biologists at the California Institute of Technology has found that, in mouse models, the molecule microRNA-146a acts as a critical regulator and protector of blood-forming stem cells (called hematopoietic stem cells, or HSCs) during chronic inflammation, suggesting that a deficiency of miR-146a may be one important cause of blood cancers and bone marrow failure.

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Bringing a New Stem Cell Treatment to Cancer Patients: Dr. Karen Aboody, M.D. at TEDxAJU

By on Monday, May 20th, 2013 | No Comments

Dr. Aboody is an Associate Professor both in the Department of Neurosciences and Division of Neurosurgery at City of Hope. Her research focuses on using stem…

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Adult cells transformed into early-stage nerve cells, bypassing the pluripotent stem cell stage

By on Friday, May 3rd, 2013 | No Comments

Scientists have converted skin cells from people and monkeys into a cell that can form a wide variety of nervous-system cells — without passing through the do-it-all stage called the induced pluripotent stem cell, or iPSC.

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Researchers look to mathematics, nature, to understand the immune system and its role in cancer

By on Wednesday, May 1st, 2013 | No Comments

Can patterns in tree branches or the meandering bends in a river provide clues that could lead to better cancer therapies? According to a new study, these self-similar, repeating patterns in nature known as fractals help scientists better understand how the immune system is organized and may one day be used to help improve stem cell transplant outcomes in leukemia patients by predicting the probability of transplant complications.

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Studying The Effect Of Stem Cell Therapy On Cancer

By on Tuesday, April 30th, 2013 | No Comments

Injection of human stem cells into mice with tumors slowed down tumor growth, finds research published in BioMed Central’s open access journal Stem Cell Research & Therapy. Human mesenchymal stem cells (MSC), isolated from bone marrow, caused changes in blood vessels supplying the tumor, and it is this modification of blood supply which seems to impact tumor growth…

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Clarifying the effect of stem cell therapy on cancer

By on Monday, April 29th, 2013 | No Comments

Injection of human stem cells into mice with tumors slowed down tumor growth, finds new research. Human mesenchymal stem cells, isolated from bone marrow, caused changes in blood vessels supplying the tumor, and it is this modification of blood supply which seems to impact tumor growth.

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Toxicity profile informs decision on preferred conditioning regimen in autologous transplant for neuroblastoma

By on Wednesday, April 24th, 2013 | No Comments

The stem cell transplant regimen that was commonly used in the United States to treat advanced neuroblastoma in children appears to be more toxic than the equally effective regimen employed in Europe and Egypt, according to a new study.

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Majority of children readmitted to hospital following stem cell transplant

By on Wednesday, April 24th, 2013 | No Comments

Almost two-thirds of children who receive stem cell transplants are readmitted to the hospital within six months, according to new research.

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Method makes it easier to separate useful stem cells from ‘problem’ ones for therapies

By on Tuesday, April 23rd, 2013 | No Comments

Pluripotent stem cells can turn (differentiate) into any cell type in the body, such as nerve, muscle or bone, but inevitably some of these stem cells fail to differentiate and end up mixed in with their newly differentiated daughter cells. Scientists have discovered a new agent that may be useful in strategies to kill off pluripotent stem cells from differentiated daughter cells.

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