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Posts Tagged ‘spectrometry’


AZD0530 in Treating Patients With Metastatic or Locally Advanced Breast Cancer That Cannot Be Removed By Surgery

Condition :   Breast Cancer Interventions :   Drug: saracatinib;   Other: immunoenzyme technique;   Other: laboratory biomarker analysis;   Other: pharmacological study;   Other: spectrometry Sponsors :   National Cancer Institute (NCI);   Memorial Sloan-Kettering Cancer Center;   National Cancer Institute (NCI) Completed – verified July 2009

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Biomarkers in Predicting Treatment Response in Samples From Patients With Early-Stage Non-Small Cell Lung Cancer Previously Treated With Adjuvant Chemotherapy

Condition :   Lung Cancer Interventions :   Genetic: gene expression analysis;   Genetic: microarray analysis;   Genetic: mutation analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: laboratory biomarker analysis;   Other: mass spectrometry;   Other: medical chart review Sponsors :   National Cancer Institute (NCI);   NCIC Clinical Trials Group;   National Cancer Institute (NCI) Not yet recruiting – verified May 2012

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Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas

Conditions :   Chordoma;   Desmoid Tumor;   Sarcoma Interventions :   Genetic: DNA analysis;   Genetic: microarray analysis;   Genetic: polymerase chain reaction;   Other: laboratory biomarker analysis;   Other: mass spectrometry Sponsors :   Children’s Oncology Group;   National Cancer Institute (NCI) Active, not recruiting – verified March 2012

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Linsitinib in Treating Patients With Asymptomatic or Mildly Symptomatic Metastatic Prostate Cancer

Condition :   Prostate Cancer Interventions :   Drug: linsitinib;   Genetic: RNA analysis;   Other: circulating tumor cell analysis;   Other: enzyme-linked immunosorbent assay;   Other: laboratory biomarker analysis;   Other: liquid chromatography;   Other: mass spectrometry Sponsors :   Case Comprehensive Cancer Center;   National Cancer Institute (NCI) Recruiting – verified February 2012

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A Conversation with Drs. Christopher Kinsinger and Henry Rodriguez about Sharing Proteomics Data

Last September, NCI’s Office of Cancer Clinical Proteomics Research convened a workshop of researchers and stakeholders in the field of proteomics to discuss ways to better share data about the structure and functions of proteins—a challenge facing the entire proteomics community. The meeting, held in Sydney, Australia, addressed establishing standards to ensure the quality of the data, particularly those generated by a technique known as mass spectrometry. A meeting report with recommendations for the field was recently published simultaneously in four journals simultaneously.

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Role of Biomarkers in Disease Progression in Samples From Patients With Acute Myeloid Leukemia

Condition :   Leukemia Interventions :   Genetic: gene expression analysis;   Genetic: gene rearrangement analysis;   Genetic: polymerase chain reaction;   Genetic: protein analysis;   Genetic: western blotting;   Other: laboratory biomarker analysis;   Other: mass spectrometry Sponsors :   Children’s Oncology Group;   National Cancer Institute (NCI) Active, not recruiting – verified December 2011

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Biomarker in Blood and Tissue Samples From Patients With Newly Diagnosed Neuroblastoma

Condition :   Neuroblastoma Interventions :   Genetic: RNA analysis;   Genetic: polymerase chain reaction;   Genetic: protein expression analysis;   Genetic: proteomic profiling;   Genetic: western blotting;   Other: enzyme-linked immunosorbent assay;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis;   Other: liquid chromatography;   Other: mass spectrometry Sponsors :   Children’s Oncology Group;   National Cancer Institute (NCI) Active, not recruiting – verified June 2011

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Resveratrol in Postmenopausal Women With High Body Mass Index

Condition :   Healthy, no Evidence of Disease Interventions :   Drug: resveratrol;   Other: enzyme-linked immunosorbent assay;   Other: high performance liquid chromatography;   Other: laboratory biomarker analysis;   Other: mass spectrometry Sponsors :   University of Arizona;   National Cancer Institute (NCI) Not yet recruiting – verified June 2011

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Biomarker Expression in Samples From Young Patients With Anaplastic Large Cell Lymphoma

Condition :   Lymphoma Interventions :   Genetic: microarray analysis;   Genetic: protein expression analysis;   Genetic: western blotting;   Other: flow cytometry;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis;   Other: mass spectrometry Sponsors :   Children’s Oncology Group;   National Cancer Institute (NCI) Active, not recruiting – verified June 2011

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Defined Green Tea Catechin Extract in Treating Patients With Localized Prostate Cancer Undergoing Surgery

Conditions :   Stage I Prostate Cancer;   Stage IIA Prostate Cancer;   Stage IIB Prostate Cancer Interventions :   Dietary Supplement: defined green tea catechin extract;   Other: placebo;   Other: immunohistochemistry staining method;   Other: immunoenzyme technique;   Other: questionnaire administration;   Procedure: therapeutic conventional surgery;   Other: high performance liquid chromatography;   Other: mass spectrometry Sponsors :   Case Comprehensive Cancer Center;   National Cancer Institute (NCI) Recruiting – verified April 2011

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