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Posts Tagged ‘samples’


In Pediatric Bone Cancer, K9 Osteosarcoma Samples Identify Drivers Of Metastasis

Human osteosarcoma samples are hard to come by, making the disease difficult to study. However, K9 bone cancer is genetically indistinguishable from the human form of the disease, and over 10,000 canine patients develop the disease every year…

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Investigation Continues in Paterson, NJ Asbestos Incident

As authorities in Paterson, New Jersey continue to investigate why prison inmates and untrained municipal employees were charged with the task of removing asbestos materials from municipal offices that were undergoing renovation, the city has finally decided to seek out a private licensed contractor to remove and disposal of the toxic debris. “This is part of being in compliance with what (the state) requested,” Paterson Public Works Director Christopher Coke said, noting that the city council will meet next week to vote on a resolution that charges them with the task of gathering bids to complete the project. In the meantime, many still wonder what city officials were thinking when they drafted inmates and employees not licensed to handle asbestos to start the job several months ago. The city’s law department and the state’s labor department have confirmed that they are involved in the investigation as is Sheriff Richard Berdnik, who is interested in learning the facts because the inmates used in the project were part of his Sheriff’s Labor Assistance Program (SLAP). “Our guys weren’t equipped to do that and we weren’t educated to do that,” said Michael Jackson, a member of the executive board of American Federation of State, County and Municipal Employees, Local 2272, referring to the municipal workers. “The city tried to cut costs and it put people in danger.” Coke claims, however, that the workers were never in danger of asbestos exposure . He says all employees were given masks and gloves while working inside the Ellison Street structure and that air and dust samples were taken and came back negative. Others say that Coke brought in a fan to clear the dust before the samples were taken. Now, the inmates and municipal workers remain worried about their health, aware that inhaling asbestos fibers could eventually cause severe respiratory problems and issues such as the development of mesothelioma cancer .

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Investigation Continues in Paterson, NJ Asbestos Incident

As authorities in Paterson, New Jersey continue to investigate why prison inmates and untrained municipal employees were charged with the task of removing asbestos materials from municipal offices that were undergoing renovation, the city has finally decided to seek out a private licensed contractor to remove and disposal of the toxic debris. “This is part of being in compliance with what (the state) requested,” Paterson Public Works Director Christopher Coke said, noting that the city council will meet next week to vote on a resolution that charges them with the task of gathering bids to complete the project. In the meantime, many still wonder what city officials were thinking when they drafted inmates and employees not licensed to handle asbestos to start the job several months ago. The city’s law department and the state’s labor department have confirmed that they are involved in the investigation as is Sheriff Richard Berdnik, who is interested in learning the facts because the inmates used in the project were part of his Sheriff’s Labor Assistance Program (SLAP). “Our guys weren’t equipped to do that and we weren’t educated to do that,” said Michael Jackson, a member of the executive board of American Federation of State, County and Municipal Employees, Local 2272, referring to the municipal workers. “The city tried to cut costs and it put people in danger.” Coke claims, however, that the workers were never in danger of asbestos exposure . He says all employees were given masks and gloves while working inside the Ellison Street structure and that air and dust samples were taken and came back negative. Others say that Coke brought in a fan to clear the dust before the samples were taken. Now, the inmates and municipal workers remain worried about their health, aware that inhaling asbestos fibers could eventually cause severe respiratory problems and issues such as the development of mesothelioma cancer .

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Contaminant Levels Recommended By EU Exceeded In Some Cheeses

Researchers at the University of Las Palmas de Gran Canaria (Spain) have analysed more than 60 brands of cheese commonly available in supermarkets. The concentration of organochloride contaminants in the majority of the samples was lower than levels set by European legislation, but in a few cases it was higher…

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MD Anderson study finds blood vessel cells coax colorectal cancer cells into more dangerous state

Blood vessels that supply oxygen and nutrients to tumors can also deliver something else — a signal that strengthens nearby cancer cells, making them more resistant to chemotherapy, more likely to spread to other organs and more lethal, scientists at The University of Texas MD Anderson Cancer Center report online in Cancer Cell. Working in human colorectal cancer cell lines and tumor samples, as well as mouse models, the researchers found that endothelial cells, which line the inside of blood vessels, can trigger changes in cancer cells without even coming into direct contact with them.

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Next lung cancer treatment advancement may come in the form of informatics

Bioinformatic experts are creating a new model based on digital images and genomics to help improve survival rates in people with lung cancer, which is the leading cancer killer among men and women in the United States. The model – which will help clinicians select the treatment most likely to be successful – will base some of its data on a repository of 4,000 lung cancer samples from the Appalachian region, an area that has higher rates of lung cancer than anywhere else in the nation.

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Beth Israel study finds a ‘code of silence’ in acute myeloid leukemia

The development of acute myeloid leukemia (AML) is associated with a variety of genetic changes. Some of these alterations are epigenetic, wherein the sequence of the genes is unchanged, but chemical modifications to the DNA alter gene expression. In a study published in the Journal of Clinical Investigation, researchers led by Beth Israel Deaconess Medical Center found that a transcriptional regulator known as C/EBPG was highly expressed in a subset of AML samples that had an epigenetically silenced C/EBPA gene. The Beth Israel Deaconess Medical Center is a component of the Dana-Farber Cancer Institute.

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Statistical Image Analysis Method Offers Automatic Mitotic Cell Detection For Breast Cancer Diagnosis

Scientists have developed a statistical image analysis method which can assist in the grading of breast cancer by automatically segmenting tumour regions and detecting dividing cells in tissue samples…

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On The Hunt For Rare Cancer Cells

Jellyfish-inspired device that rapidly and efficiently captures cancer cells from blood samples could enable better patient monitoring. Tumor cells circulating in a patient’s bloodstream can yield a great deal of information on how a tumor is responding to treatment and what drugs might be more effective against it…

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Johns Hopkins researchers find that laser-light testing of breast tumor fiber patterns helps show whose cancer is spreading

New diagnostic tool could lower numbers of unnecessary lymph node surgeries. Using advanced microscopes equipped with tissue-penetrating laser light, cancer imaging experts at Johns Hopkins have developed a promising, new way to accurately analyze the distinctive patterns of ultra-thin collagen fibers in breast tumor tissue samples and to help tell if the cancer has spread.

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