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Posts Tagged ‘pre’


Preclinical tests shows agent stops ‘slippery’ proteins from binding, causing Ewing sarcoma

Continuous infusion of a novel agent not only halted the progression of Ewing sarcoma in rats, while some tumors also regressed to the point that cancer cells could not be detected microscopically, say researchers at Georgetown Lombardi Comprehensive Cancer Center. Their study, which will be presented at the 2013 annual meeting of the American Society of Clinical Oncology, provides pre-clinical evidence necessary to initiate a clinical trial.

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Stronger by Mchalie while fighting Leukemia

Mchalie was diagnosed with leukemia (ALL Pre-B Cell) on November 26th/27th, 2013. She started treatment on the 28th. Today marked 5 months into her battle. S…

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Dad’s genome more ready at fertilization than mom’s is — but hers catches up

Researchers have discovered that while the genes provided by the father arrive at fertilization pre-programmed to the state needed by the embryo, the genes provided by the mother are in a different state and must be reprogrammed to match.

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Study shows advantage to nanotech delivery of therapy for breast cancer brain metastases

Breast cancer brain metastases present a challenge to clinicians because there are few systemic therapies capable of crossing the blood-brain barrier to control the disease. An international team, led by scientists at the University of North Carolina Lineberger Comprehensive Cancer Center, reports pre-clinical research showing improved efficacy of a PEGylated liposomal (encapsulated) anti-cancer agent compared with a non-liposomal formulation of the same drug in an intracranial model of breast cancer.

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Novel monoclonal antibody inhibits tumor growth in breast cancer and angiosarcoma

A monoclonal antibody targeting a protein known as SFPR2 has been shown to inhibit tumor growth in pre-clinical models of breast cancer and angiosarcoma.

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IBM Watson Demo: Oncology Diagnosis and Treatment (2 min.)

The IBM Watson Cancer Diagnosis and Treatment Adviser demo was created in close collaboration with Memorial Sloan Kettering, one of the world’s preeminent cancer treatment and research institutions. The demo scenario follows the interactions of a hypothetical oncologist and patient as they move through consultations, tests, treatment options, patient preferences and pre-authorization. It showcases IBM Watson’s capabilities in natural language processing, hypothesis generation and evaluation, and machine learning.

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IBM Watson Demo: Oncology Diagnosis and Treatment (2 min.)

The IBM Watson Cancer Diagnosis and Treatment Adviser demo was created in close collaboration with Memorial Sloan Kettering, one of the world’s preeminent cancer treatment and research institutions. The demo scenario follows the interactions of a hypothetical oncologist and patient as they move through consultations, tests, treatment options, patient preferences and pre-authorization. It showcases IBM Watson’s capabilities in natural language processing, hypothesis generation and evaluation, and machine learning.

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The Long-Term Efficacy Of Minimally Invasive Therapy For Patients With Barrett’s Esophagus

According to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, patients with Barrett’s esophagus and early or pre-cancerous cells have been shown to significantly benefit from minimally invasive therapy delivered through an endoscope – a medical instrument used to look inside an organ or cavity in the body…

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Diet of resistant starch helps the body resist colorectal cancer

New research shows that resistant starch helps the body resist colorectal cancer through mechanisms including killing pre-cancerous cells and reducing inflammation that can otherwise promote cancer.

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Thomas Jefferson University researchers discover new pathways that drive metastatic prostate cancer

Elevated levels of Cyclin D1b could function as a novel biomarker of lethal metastatic disease in prostate cancer patients, according to a pre-clinical study published ahead of print on December 21 in the Journal of Clinical Investigation by researchers at the Kimmel Cancer Center at Jefferson.

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