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Posts Tagged ‘mismatch’


DNA mismatch repair happens only during a brief window of opportunity

In eukaryotes-the group of organisms that include humans –- a key to survival is the ability of certain proteins to quickly and accurately repair genetic errors that occur when DNA is replicated to make new cells. Researchers have solved part of the mystery of how these proteins do their job, a process called DNA mismatch repair.

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Gene Mutations Associated with Lethal Prostate Cancers Identified through Exome Sequencing

… addition found that a subset of prostate cancer tumors exhibit hypermutated genomes, which may be … out. However, they add, “cancers in the colon with mismatch repair gene defects and those …

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DNA repair system affects colon cancer recurrence and survival

Colorectal cancer patients with defects in mismatch repair — one of the body’s systems for repairing DNA damage — have lower recurrence rates and better survival rates than patients without such defects, according to a new study.

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Genetics and Bowel Cancer: New bowel cancer evidence calls for routine DNA repair test

… Bowel cancer patients whose tumors contain defects in specific … post-surgery bowel cancer patients, have confirmed that colon tumors containing defects in their DNA mismatch …

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New bowel cancer evidence supports calls for routine DNA damage repair test

… Bowel cancer patients whose tumours contain defects in specific … post-surgery bowel cancer patients, have confirmed that colon tumors containing defects in their DNA mismatch …

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