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Posts Tagged ‘lenalidomide’


New Combination Therapy for Untreated Multiple Myeloma

In this phase II trial, people with newly diagnosed multiple myeloma will be treated with carfilzomib, lenalidomide, and dexamethasone for eight 28-day treatment cycles.

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Treating Patients with High-Risk Smoldering Myeloma

In this phase III clinical trial, patients with smoldering myeloma classified as high risk for progression will be randomly assigned to undergo standard observation or six 4-week courses of treatment with the drug lenalidomide.

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Treating Patients with High-Risk Smoldering Myeloma

In this phase III clinical trial, patients with smoldering myeloma classified as high risk for progression will be randomly assigned to undergo standard observation or six 4-week courses of treatment with the drug lenalidomide.

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Lenalidomide Maintenance Therapy for Multiple Myeloma

Condition :   Multiple Myeloma Intervention :   Drug: Lenalidomide Sponsors :   National Institutes of Health Clinical Center (CC);   National Cancer Institute (NCI);   Celgene Corporation Recruiting – verified August 2012

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Phase II Study of Subcutaneous (SC) Bortezomib, Lenalidomide and Dexamethasone for Relapsed and/or Refractory Multiple Myeloma; Followed by SC Bortezomib Maintenance

Condition :   Multiple Myeloma Interventions :   Drug: Bortezomib;   Drug: Lenalidomide;   Drug: Dexamethasone Sponsors :   National Institutes of Health Clinical Center (CC);   National Cancer Institute (NCI);   Millennium Pharmaceuticals, Inc. Recruiting – verified July 2012

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Lenalidomide, Rituximab, and PI3K Delta Inhibitor CAL-101 in Treating Patients With Recurrent Follicular Non-Hodgkin Lymphoma

Condition :   Lymphoma Interventions :   Biological: rituximab;   Drug: PI3K delta inhibitor CAL-101;   Drug: lenalidomide Sponsors :   National Cancer Institute (NCI);   Cancer and Leukemia Group B;   National Cancer Institute (NCI) Not yet recruiting – verified July 2012

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Clofarabine Followed By Lenalidomide for High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia

Conditions :   Myeldysplastic Syndrome (MDS);   Chronic Myelomonocytic Leukemia;   Bone Marrow Diseases;   Neutropenia;   Acute Myeloid Leukemia (AML) Interventions :   Drug: Clofarabine;   Drug: Lenalidomide Sponsors :   National Institutes of Health Clinical Center (CC);   National Heart, Lung, and Blood Institute (NHLBI) Recruiting – verified May 2012

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Natural Killer (NK) Cells in Cord Blood Transplantation

Conditions :   Leukemia;   Chronic Lymphocytic Leukemia Interventions :   Drug: Lenalidomide;   Drug: Fludarabine monophosphate;   Drug: Melphalan;   Procedure: NK Infusion;   Procedure: CB Infusion Sponsors :   M.D. Anderson Cancer Center;   M.D. Anderson Cancer Center Not yet recruiting – verified June 2012

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Autologous Stem Cell Transplantation and Maintenance Therapy for Multiple Myeloma

Condition :   Multiple Myeloma Interventions :   Drug: Melphalan;   Drug: Lenalidomide Sponsors :   University of Virginia;   University of Virginia Recruiting – verified June 2012

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Phase I Study of Lenalidomide in Patients With Acute Leukemia

Condition :   Acute Leukemia Intervention :   Drug: Lenalidomide Sponsors :   University of California, Davis;   University of California, Davis;   Celgene Corporation Not yet recruiting – verified June 2012

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