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Blocking A Single Gene Renders Tumors Less Aggressive

By on Monday, May 6th, 2013 | No Comments

Researchers at Johns Hopkins have identified a gene that, when repressed in tumor cells, puts a halt to cell growth and a range of processes needed for tumors to enlarge and spread to distant sites. The researchers hope that this so-called “master regulator” gene may be the key to developing a new treatment for tumors resistant to current drugs…

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Stem Cells Derived from Fat Tissue May be Used in the Future for Mesothelioma Treatment

By on Monday, April 22nd, 2013 | No Comments

Stem cell research is one area that has shown promise in the fight against cancer. Last year researchers at the University of Cincinnati Cancer Center reported that lung cancer stem cells can lead to a “new avenue” for immunotherapy treatment options that specifically target stem cells. Now, researchers at Johns Hopkins have found that using …

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Stem Cells Derived from Fat Tissue May be Used in the Future for Mesothelioma Treatment

By on Monday, April 22nd, 2013 | No Comments

Stem cell research is one area that has shown promise in the fight against cancer. Last year researchers at the University of Cincinnati Cancer Center reported that lung cancer stem cells can lead to a “new avenue” for immunotherapy treatment options that specifically target stem cells. Now, researchers at Johns Hopkins have found that using …

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DNA-Damaging Toxins Discovered In Common Plant-Based Foods – Liquid Smoke, Black And Green Teas And Coffee

By on Monday, April 1st, 2013 | No Comments

In a laboratory study pairing food chemistry and cancer biology, scientists at the Johns Hopkins Kimmel Cancer Center tested the potentially harmful effect of foods and flavorings on the DNA of cells. They found that liquid smoke flavoring, black and green teas and coffee activated the highest levels of a well-known, cancer-linked gene called p53…

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Researchers Use Of A Type Of Stem Cells From Human Adipose Tissue To Chase Migrating Glioblastoma Cells

By on Thursday, March 14th, 2013 | No Comments

In laboratory studies, Johns Hopkins researchers say they have found that stem cells from a patient’s own fat may have the potential to deliver new treatments directly into the brain after the surgical removal of a glioblastoma, the most common and aggressive form of brain tumor…

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Protein Uses Multiple Means To Help Cells Cope When Oxygen Runs Low

By on Tuesday, February 26th, 2013 | No Comments

A protein known for turning on genes to help cells survive low-oxygen conditions also slows down the copying of new DNA strands, thus shutting down the growth of new cells, Johns Hopkins researchers report…

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Consistent Personal Epigenetic ‘Signatures’ Discovered In Prostate Cancer Patients’ Metastases

By on Sunday, January 27th, 2013 | No Comments

In a genome-wide analysis of 13 metastatic prostate cancers , scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic “signatures” across all metastatic tumors in each patient.

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Johns Hopkins develops updated tool to predict prostate cancer spread

By on Sunday, January 6th, 2013 | No Comments

Prostate cancer experts at Johns Hopkins have developed an updated version of the Partin Tables, a tool to help men diagnosed with prostate cancer and their doctors to better assess their chance of a surgical cure. The updated tool, based on a study of more than 5,600 men treated at The Johns Hopkins Hospital from 2006 to 2011, is published in the Jan. 3 issue of the British Journal of Urology International. Johns Hopkins is home to the Sidney Kimmel Comprehensive Cancer Center.

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Best Practices Can Reduce Central-Line Infections in Children with Cancer

By on Wednesday, September 19th, 2012 | No Comments

By using best practices, health providers at Johns Hopkins Children’s Center reduced central line-associated bloodstream infections by 20 percent over 2 years, according to a study published in Pediatrics.

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Genome wide scan maps mutations in deadly lung cancers

By on Friday, September 7th, 2012 | No Comments

Scientists have completed a comprehensive map of genetic mutations linked to an aggressive and lethal type of lung cancer. Among the errors found in small cell lung cancers, the team of scientists, including those at the Johns Hopkins Kimmel Cancer Center, found an alteration in a gene called SOX2 associated with early embryonic development. The team also included scientists from the University of Texas Southwestern Medical Center, the University of Colorado Cancer Center, and Genentech.

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