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Scheduled imaging studies provide little help detecting relapse of aggressive lymphoma

By on Sunday, May 19th, 2013 | No Comments

Imaging scans following treatment for diffuse large B-cell lymphoma do little to help detect a relapse, a Mayo Clinic study has found. The overwhelming majority of patients with this aggressive lymphoma already have symptoms, an abnormal physical exam or an abnormal blood test at the time of relapse, the researchers say. The findings will be presented at the American Society of Clinical Oncology annual meeting May 31-June 4 in Chicago.

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Skin cancer linked to reduced risk for Alzheimer’s disease

By on Friday, May 17th, 2013 | No Comments

People who have non-melanoma skin cancer may be less likely to develop Alzheimer’s disease, according to research carried out by scientists at Albert Einstein College of Medicine of Yeshiva University (home to the Albert Einstein Cancer Center). Their findings were published in the May 15, 2013 online issue of Neurology, the journal of the American Academy of Neurology.

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First prospective trial shows molecular profiling timely for tailoring therapy

By on Thursday, May 16th, 2013 | No Comments

CUSTOM is the first completed prospective clinical trial that used genetic analysis alone to assign cancer treatment for patients with one of three different cancers. Findings suggest patients, and their physicians, are eager to jump into next-era cancer care — analysis of an individual’s tumor to find and target genetic mutations that drive the cancer.

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Study IDs key protein for cell death

By on Wednesday, May 15th, 2013 | No Comments

Findings may offer a new way to kill cancer cells by forcing them into an alternative programmed-death pathway.

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4 New Genetic Risk Factors Identified For Testicular Cancer

By on Tuesday, May 14th, 2013 | No Comments

A new study looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer, the most commonly diagnosed type in young men today. The findings from this first-of-its-kind meta-analysis were reported online in Nature Genetics by researchers at the Perelman School of Medicine at the University of Pennsylvania…

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Agent orange exposure linked to life-threatening prostate cancer

By on Monday, May 13th, 2013 | No Comments

A new analysis has found a link between exposure to Agent Orange and lethal forms of prostate cancer among US Veterans. The findings suggest that Agent Orange exposure history should be incorporated into prostate screening decisions for Veterans.

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Egg Genome Is Reprogrammed To Match Sperm’s With Or Without A Paternal Genome

By on Monday, May 13th, 2013 | No Comments

Researchers from Huntsman Cancer Institute (HCI) at the University of Utah have discovered that while the genes provided by the father arrive at fertilization pre-programmed to the state needed by the embryo, the genes provided by the mother are in a different state and must be reprogrammed to match. The findings have important implications for both developmental biology and cancer biology…

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Genetic variations associated with susceptibility to bacteria linked to stomach disorders

By on Wednesday, May 8th, 2013 | No Comments

Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter pylori, a bacteria that is a major cause of gastritis and stomach ulcers and is linked to stomach cancer, findings that may help explain some of the observed variation in individual risk for H pylori infection.

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Case Western researchers develop a novel method to disrupt a cancer growth signaling pathway

By on Sunday, May 5th, 2013 | No Comments

A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine (home of the Case Comprehensive Cancer Center) have developed a novel method to disrupt this growth signaling pathway, with findings that suggest a new treatment for breast, colon, melanoma and other cancers. The research team has pinpointed the cancer abnormality to a mutation in a gene called PIK3CA that results in a mutant protein, which may be an early cancer switch.

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Discovery Of Markers Related To Ovarian Cancer Survival And Recurrence

By on Wednesday, May 1st, 2013 | No Comments

Researchers at the University of Illinois have identified biomarkers that can be used to determine ovarian cancer survival and recurrence, and have shown how these biomarkers interact with each other to affect these outcomes. Their findings appear in the journal PLOS ONE…

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