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Posts Tagged ‘factor’


Scientists discover how a protein finds its way

Scientists have uncovered how an enzyme co-factor can bestow specificity on a class of proteins with otherwise nonspecific biochemical activity. Proteins can have more than one function, but they often need to be very specific in their action or they create cellular havoc, possibly leading to disease.

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Unique Mechanism Identified By Which Glioblastoma Cells Develop Resistance To Drugs That Target EGFR Signaling

Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor (EGFR), fuels a wide variety of cancers – including a highly malignant brain cancer known as glioblastoma…

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Medical enigma: The healing element is also the enemy

The same factor in our immune system that is instrumental in enabling us to fight off severe and dangerous inflammatory ailments is also a player in doing the opposite at a later stage, causing the suppression of our immune response. Why and how this happens and what can be done to mediate this process for the benefit of humankind is the subject of a new article.

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Immune system: The healing element is also the enemy

The same factor in our immune system that is instrumental in enabling us to fight off severe and dangerous inflammatory ailments is also a player in doing the opposite at a later stage, causing the suppression of our immune response.

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Hope for stopping melanoma from spreading

Inhibition of the protein known as adenosine diphosphate ribosylation factor 6 (ARF6) reduces the spread of melanoma to the lungs in mice, according to a new study.

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Scientists discover how to shutdown cancer’s powerful master protein

The powerful master regulatory transcription factor called Bcl6 is key to the survival of a majority of aggressive lymphomas, which arise from the B-cells of the immune system. The protein has long been considered too complex to target with a drug since it is also crucial to the healthy functioning of many immune cells in the body, not just B cells gone bad.

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New Angle To Combat Malignant Brain Tumors In Children

A medulloblastoma is a malignant brain tumor that occurs primarily in children and is currently untreatable. Peter Carmeliet and his team (VIB-KU Leuven) joined forces with scientists at Massachusetts General Hospital in Harvard to study the role of the placental growth factor (PIGF) in the growth of this brain tumor…

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Cholangiocarcinoma: The Next Asbestos-Related Disease?

Researchers from the University of Bologna noted that many of their cholangiocarcinoma patients had a history of asbestos exposure. In a recent study to further investigate the correlation, they found that asbestos exposure may be an occupational risk factor for cholangiocarcinoma.

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Microscopy technique could be key to improving cancer treatments with targeted therapeutic drugs

For scientists to improve cancer treatments with targeted therapeutic drugs, they need to be able to see proteins prevalent in the cancer cells. This has been impossible, until now. Thanks to a new microscopy technique, medical researchers have now observed how clusters of epidermal growth factor receptor (EGFR) — a protein abundant in lung and colon cancers, glioblastoma and others — malfunctions in cancer cells.

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what is EGFR Lung Cancer

what is EGFR Lung Cancer Epidermal growth factor receptor

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