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Posts Tagged ‘ensure’


Mitochondrial Metabolic Regulator SIRT4 Guards Against DNA Damage

Healthy cells don’t just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them. Researchers studying a set of proteins that regulate physiology, caloric restriction and aging have discovered another important role that one of them plays…

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Albany Company Faces Large Fine for "Willful" Asbestos Violations

When investigators from the U.S. Department of Labor’s Occupational Health and Safety Administration visited a construction project on Albany’s Kent Street, what they found made them fear for the safety of the workers there. That’s because the employer in charge, Lorice Enterprise, allowed them to work among dangerous asbestos dust, showing little regard for their health. As a result, OSHA has issued nine violations against Lorice Enterprise, also of Albany, New York , based on the inspection of that particular property. The report by OSHA investigators deemed that “Lorice Enterprises did not conduct an initial exposure assessment to determine exposure for the workers removing asbestos-containing roofing material. Additionally, the employer did not utilize wet methods to ensure that asbestos did not become airborne, and failed to ensure head and eye protection for these workers,” said Kimberly Castillon , OSHA’s Albany area director. At least one of the violations, failure to measure potential daily asbestos exposure , is considered a “willful” violation, which means that the company knew that what they were doing was wrong. OSHA describes a willful violation as an “intentional, knowing or voluntary disregard for the law’s requirements, or with plain indifference to worker safety and?health.” The situation is alarming because asbestos is a known carcinogen and inhalation of its tiny, sharp fibers can result in the formation of tumors, usually in the lining of the lungs, known as the pleura. These tumors result in the development of malignant pleural mesothelioma , a very aggressive cancer. Those who suffer asbestos exposure may also develop the less-serious asbestosis or other respiratory-related diseases. Lorice Enterprise faces fines of up to $83,000, reports an article in the Albany Times Union. The company has two weeks to respond to the allegations, request a meeting with the area OSHA director, or to contest the citations and the penalties that go along with them.

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UCSD study illuminates how cells know when it’s time to eat themselves

Researchers at the University of California, San Diego School of Medicine and the Moores Comprehensive Cancer Center have identified a molecular mechanism regulating autophagy, a fundamental stress response used by cells to help ensure their survival in adverse conditions. The researchers report that an enzyme called AMPK, typically involved in sensing and modulating energy use in cells, also regulates autophagic enzymes. Failure of normal autophagy has been associated with accumulated cell damage and aging.

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How cells know when it’s time to eat themselves

Researchers have identified a molecular mechanism regulating autophagy, a fundamental stress response used by cells to help ensure their survival in adverse conditions.

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Earthquake Ravaged New Zealand Homes Pose ‘Health Landmine’ As Damaged Asbestos Ceilings Sealed

In what is potentially brewing to be a health crisis on a significant level, officials in Christchurch, New Zealand are calling for ‘encasing’ damaged asbestos ceilings instead of removing. Over 4,000 homes damaged by an earthquake may have the crumbling asbestos ceilings sealed over by plaster. Many homeowners fear that public officials may not even inform the community which homes have had this procedure done, further compounding the issue. According to Alistair Humphrey , a Canterbury District Health Board medical official, sealing over the damaged asbestos ceiling with plaster will create a medical perfect storm. Humphrey is concerned over the ‘out of sight, out of mind’ mentality ruling community leaders. Covering up the asbestos “disguises the fact that it is there,” potentially creating a health “landmine,” said Humphrey. Removing the damaged asbestos is the only surefire way to ensure that the public at large is protected against unintentional asbestos exposure which could lead to devastating diseases. Asbestos is a highly toxic and carcinogenic natural material heavily used in building and plumbing supply manufacturing. Until use of the material was banned, asbestos was an inexpensive alternative to other building material, prized for its durability, heat resistance and insulating properties. Exposure even to a small amount of friable or damaged asbestos can lead to severe medical conditions including breathing complications, internal damage and the development of cancer. Most severe of the health complications associated with asbestos exposure is mesothelioma , a rare form of cancer that affects the delicate lining of the lungs, heart and abdominal cavity. When asbestos is damaged, small particles are released into the air making it easier to inhale. These small asbestos particles then travel through the lungs and embed into the pleura or the delicate lining that protects the lungs. Though damage to the pleura of the lungs is the most common effect of asbestos exposure , some asbestos particles can travel to the pleura of the heart or abdominal cavity. Humphrey is concerned that if the practice of sealing the damaged asbestos ceilings with plaster continues, it poses a significant health threat for future homeowners. “In the future, no one will know asbestos is there. It is covered over,” he said. Humphrey warned that a homeowner looking to renovate their house may accidentally uncover the hidden asbestos and expose themselves. Removing the asbestos is the only way to ensure safety. The Earthquake Commission , who is overseeing the project, defends the sealing practice, stating that only undamaged asbestos ceilings are sealed.

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How hepatitis C virus reprograms human liver cells

Hepatitis C virus has evolved to invade and hijack the basic machinery of the human liver cell to ensure its survival and spread. Researchers have discovered how hepatitis C binds with and re-purposes a basic component of cellular metabolism known as a microRNA to help protect and replicate the virus.

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NCI Central Institutional Review Board Receives Accreditation

The Association for the Accreditation of Human Research Protection Programs has awarded the NCI Central Institutional Review Board full accreditation. AAHRPP awards accreditation to organizations demonstrating the highest ethical standards in clinical research. Achieving accreditation establishes that the NCI CIRB has robust review processes in place to ensure the safety and protection of people who participate in NCI-funded clinical studies.

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Risk Of Treatment Failure And Death Following Deviation From Radiation Protocols

Implementing measures to ensure radiation therapy protocols are followed not only decreases deviations, but it can also improve overall survival in cancer patients, Thomas Jefferson University Hospital researchers suggest in a first-of-its kind study presented during a plenary session at the American Society for Radiation Oncology (ASTRO) 54th Annual Meeting in Boston…

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Deviating from radiation protocols increases risk of treatment failure and death in cancer patients

Implementing measures to ensure radiation therapy protocols are followed not only decreases deviations, but it can also improve overall survival in cancer patients, researchers suggest in a first-of-its kind study.

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Landmark Survey Reveals Governments Failing To Address Pandemic Of ‘Global Untreated Cancer Pain’

Governments around the world are leaving hundreds of millions of cancer patients to suffer needlessly because of their failure to ensure adequate access to pain-relieving drugs, an unprecedented new international survey reveals…

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