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Posts Tagged ‘cutaneous’

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University Of Hawaii Cancer Researchers Discover Gene Defect Responsible For Cancer Syndrome

By on Friday, September 7th, 2012 | No Comments

University of Hawai’i Cancer Center researchers have discovered germline BAP1 mutations are associated with a novel cancer syndrome characterized by malignant mesothelioma, uveal melanoma, cutaneous melanoma and atypical melanocytic tumors. Germline mutations are hereditary gene defects that are present in every cell…

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Atypical skin mole may provide means to test for new cancer syndrome

By on Thursday, September 6th, 2012 | No Comments

Researchers have discovered germline BAP1 mutations are associated with a novel cancer syndrome characterized by malignant mesothelioma, uveal melanoma, cutaneous melanoma and atypical melanocytic tumors. Germline mutations are hereditary gene defects that are present in every cell.

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Monoclonal Antibody Therapy Before Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoid Malignancies

By on Wednesday, September 5th, 2012 | No Comments

Conditions :   Adult Nasal Type Extranodal NK/T-cell Lymphoma;   Anaplastic Large Cell Lymphoma;   Angioimmunoblastic T-cell Lymphoma;   Cutaneous B-cell Non-Hodgkin Lymphoma;   Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue;   Hepatosplenic T-cell Lymphoma;   Intraocular Lymphoma;   Nodal Marginal Zone B-cell Lymphoma;   Noncutaneous Extranodal Lymphoma;   Peripheral T-cell Lymphoma;   Recurrent Adult Burkitt Lymphoma;   Recurrent Adult Diffuse Large Cell Lymphoma;   Recurrent Adult Diffuse Mixed Cell Lymphoma;   Recurrent Adult Diffuse Small Cleaved Cell Lymphoma;   Recurrent Adult Grade III Lymphomatoid Granulomatosis;   Recurrent Adult Hodgkin Lymphoma;   Recurrent Adult Immunoblastic Large Cell Lymphoma;   Recurrent Adult Lymphoblastic Lymphoma;   Recurrent Adult T-cell Leukemia/Lymphoma;   Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma;   Recurrent Grade 1 Follicular Lymphoma;   Recurrent Grade 2 Follicular Lymphoma;   Recurrent Grade 3 Follicular Lymphoma;   Recurrent Mantle Cell Lymphoma;   Recurrent Marginal Zone Lymphoma;   Recurrent Mycosis Fungoides/Sezary Syndrome;   Recurrent Small Lymphocytic Lymphoma;   Refractory Hairy Cell Leukemia;   Small Intestine Lymphoma;   Splenic Marginal Zone Lymphoma;   T-cell Large Granular Lymphocyte Leukemia;   Testicular Lymphoma;   Waldenström Macroglobulinemia Interventions :   Radiation: yttrium Y 90 anti-CD45 monoclonal antibody BC8;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation Sponsors :   Fred Hutchinson Cancer Research Center;   Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium;   National Cancer Institute (NCI) Not yet recruiting – verified August 2012

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STAT3 in T Cells: At The Crossroads of Inflammation and Cancer

By on Monday, August 13th, 2012 | No Comments

Condition :   Cutaneous T Cell Lymphoma Intervention :   Sponsors :   New York University School of Medicine;   New York University School of Medicine Recruiting – verified August 2012

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Use of sunbeds leads to over 3000 cases of melanoma a year in Europe

By on Wednesday, July 25th, 2012 | No Comments

Of 63,942 new cases of cutaneous melanoma (a form of skin cancer) diagnosed each year in Europe an estimated 3,438 (5.4 percent) are related to sunbed use. Sunbed users are at a 20 percent increased relative risk of skin cancer compared with those who have never used a sunbed. This risk doubles if they start before the age of 35 and experts warn that “tougher actions” are needed to reduce this risk.

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Multicentre Phase I Trial of Engineered T Cells for Patients With Relapsed or Refractory Primary Cutaneous CD30+ Large T Cell Lymphoma or Transformed CD30+ Mycosis Fungoides

By on Friday, July 20th, 2012 | No Comments

Conditions :   CD30 Positive Cutaneous T Cell Lymphoma;   CD30 Positive Transformed Mycosis Fungoides Intervention :   Genetic: Genetically modified T cells # 1138 Sponsors :   University of Cologne;   University of Cologne Not yet recruiting – verified July 2012

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Cutaneous human papillomavirus infection a risk factor for skin cancer

By on Tuesday, July 3rd, 2012 | No Comments

Researchers conducted a case control study and found associations between having antibodies to certain types of cutaneous human papillomavirus and a kind of skin cancer called squamous cell carcinoma. According to the researchers, evidence has been emerging that cutaneous human papillomavirus infection (not the mucosal HPV infection that is associated with cervical cancers) may be an additional risk factor for SCC.

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Sun exposure and cutaneous HPV infection found synergistic in skin cancers

By on Wednesday, June 27th, 2012 | No Comments

Researchers have found that having antibodies for cutaneous types of human papillomavirus (HPV), coupled with sun exposure (ultraviolet radiation) or poor tanning ability, can act synergistically in the development of non-melanoma skin cancers such as basal cell carcinoma (BCC) and squamous cell carcinoma (SCC).

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Smoking linked to increased risk of cutaneous squamous cell carcinoma

By on Tuesday, June 26th, 2012 | No Comments

Smoking appears to be associated with an increased risk of cutaneous squamous cell carcinoma skin cancer, according to a meta-analysis and review of available medical literature.

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Role of Proteasomes in a Dermatological Autoimmune Disease: Bullous Pemphigoid

By on Wednesday, March 21st, 2012 | No Comments

Conditions :   Pemphigoid, Bullous;   Pemphigus;   Lupus Erythematosus, Cutaneous Intervention :   Sponsor :   Centre Hospitalier Universitaire de N?mes Not yet recruiting – verified March 2012

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