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Four new genetic risk factors for testicular cancer identified

By on Sunday, May 12th, 2013 | No Comments

A new study looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer, the most commonly diagnosed type in young men today.

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Treatment Switch For Neuroblastoma Stem Cell Transplants

By on Friday, April 26th, 2013 | No Comments

The stem cell transplant regimen that was commonly used in the United States to treat advanced neuroblastoma in children appears to be more toxic than the equally effective regimen employed in Europe and Egypt, according to a new study being presented at the 26th annual meeting of the American Society of Pediatric Hematology Oncology in Miami April 24-27. The U.S…

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Toxicity profile informs decision on preferred conditioning regimen in autologous transplant for neuroblastoma

By on Wednesday, April 24th, 2013 | No Comments

The stem cell transplant regimen that was commonly used in the United States to treat advanced neuroblastoma in children appears to be more toxic than the equally effective regimen employed in Europe and Egypt, according to a new study.

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In Bladder Cancer Metastasis, A Little Molecule Makes A Big Difference

By on Friday, April 12th, 2013 | No Comments

In order to kill, bladder cancer must metastasize, most commonly to the lung – what are the differences between bladder cancers that do and do not make this deadly transition? Research presented by the Director of the University of Colorado Cancer Center at the AACR Annual Meeting 2013 shows that one big difference is a little molecule known as hsa-miR-146a…

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Cancer Cells Resistant To Cisplatin Are Sensitive To Experimental Anticancer Drugs, PARP Inhibitors

By on Friday, April 5th, 2013 | No Comments

Poly (ADP-ribose) polymerase inhibitors may be a novel treatment strategy for patients with cancer that has become resistant to the commonly used chemotherapy drug cisplatin, according to data from a preclinical study published in Cancer Research, a journal of the American Association for Cancer Research…

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New Research Suggests Friendly Bacteria May Shrink Tumours

By on Friday, April 5th, 2013 | No Comments

Friendly bacteria commonly found in probiotic drinks could be used to shrink tumours, according to new research published in the International Journal of Medical Microbiology. Researchers, from the University of Ulster in Northern Ireland and Sonidel Ltd. in Dublin, Ireland, looked at the effect on tumours of the common Lactobacillus casei. L…

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Blocking Immune Response May Enhance Viral Therapy Against Solid Tumors

By on Friday, March 15th, 2013 | No Comments

Following several years of study, investigators have found more evidence that viral therapy to treat solid tumors can be enhanced by blocking the body’s natural immune response. Oncolytic viruses have shown promise as anticancer agents, with variations of the herpes simplex virus (HSV) among the most commonly used…

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Havoc in biology’s most-used human cell line: Striking differences between HeLa genome and that of normal human cells

By on Wednesday, March 13th, 2013 | No Comments

HeLa cells are the world’s most commonly used human cell lines, and have served as a standard for understanding many fundamental biological processes. In a new study, scientists announce they have successfully sequenced the genome of a HeLa cell line. It provides a high-resolution genomic reference that reveals the striking differences between the HeLa genome and that of normal human cells. The study could improve the way HeLa cells are used to model human biology.

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Promising new drug treats and protects against radiotherapy-associated oral mucositis

By on Wednesday, March 13th, 2013 | No Comments

Mouse model studies show that administered genetically or topically, protein Smad7 protects against or heals mouth sores commonly associated with cancer treatment.

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Contaminant Levels Recommended By EU Exceeded In Some Cheeses

By on Wednesday, February 20th, 2013 | No Comments

Researchers at the University of Las Palmas de Gran Canaria (Spain) have analysed more than 60 brands of cheese commonly available in supermarkets. The concentration of organochloride contaminants in the majority of the samples was lower than levels set by European legislation, but in a few cases it was higher…

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