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Archive for the ‘Pancreatic Cancer’ Category


Rare genetic disorder provides clues to development of the pancreas

A rare genetic disorder has given researchers a surprising insight into how the pancreas develops. The finding provides a clue to how it may be possible to ‘program’ stem cells – master cells in the body that can develop into specialized cells – to become pancreatic cells.

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Dendritic cells protect against acute pancreatitis

Researchers have discovered the novel protective role dendritic cells play in the pancreas. The new study shows dendritic cells can safeguard the pancreas against acute pancreatitis, a sudden dangerous swelling and inflammation of the pancreas gland.

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Neural stem cell transplant may tackle diabetes

Researchers in Japan have discovered how a patient’s neural stem cells could be used as an alternative source of the beta cells needed for a regenerative treatment for diabetes. The research reveals how harvesting stem cells could overcome a lack of beta cell transplants from donors.

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Near-infrared imaging system shows promise as future pancreatic cancer diagnostic tool

Researchers have demonstrated for the first time that optical coherence tomography (OCT), a high resolution optical imaging technique that works by bouncing near-infrared laser light off biological tissue, can reliably distinguish between pancreatic cysts that are low-risk and high-risk for becoming malignant.

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Stem cell ‘memory’ can boost insulin levels

Scientist have now derived embryonic-like stem cells from adult stem cells that appear to retain their effectiveness in producing insulin in the human body. This research may promise a new avenue of treatment that avoids costly and dangerous pancreas transplants.

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Soft drink consumption may markedly increase risk of pancreatic cancer

Consuming two or more soft drinks per week increased the risk of developing pancreatic cancer by nearly twofold compared to individuals who did not consume soft drinks, according to a new study.

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Inflammation marker related to obesity is elevated in patients with pancreatic cancer

The levels of an inflammatory chemokine were significantly elevated in patients with pancreatic cancer who were extremely obese, according to new research.

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Predicting prognosis and treatment response in a subset of pancreatic cancer patients

Specific chemical modifications to proteins called histones, which are found in the nucleus of cells and act as spools around which DNA is wound, can be used to predict prognosis and response to treatment in subsets patients with pancreatic cancer, a new study has found.

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Researchers find oncogene is important in pancreatic cancer growth and spread

Researchers have found that PKC-iota (PKC-i), an oncogene important in colon and lung cancers, is over-produced in pancreatic cancer and is linked to poor patient survival. They also found that genetically inhibiting PKC-i in laboratory animals led to a significant decrease in pancreatic tumor growth and spread.

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ALDH associated with worse overall survival in patients with pancreatic adenocarcinoma

Expression of aldehyde dehydrogenase (ALDH) in pancreatic adenocarcinoma is associated with worse overall survival in patients who have undergone resection for early-stage disease, according to a new study.

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