Cancer News » Cancer Clinical Trials

Crizotinib Improves Progression-Free Survival in Some Patients with Advanced Lung Cancer

Tue, 18 Jun 2013 10:38:04 +0000

Results from an international phase III trial show that crizotinib (Xalkori®) substantially extends progression-free survival in previously treated patients with advanced lung cancer whose tumors have a specific genetic mutation.

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Women with Breast Cancer Micrometastases in Their Sentinel Lymph Nodes May Not Need Axillary Dissection

Wed, 01 May 2013 04:36:25 +0000

Results from a randomized clinical trial showed that women with breast cancer and only micrometastases in their sentinel lymph nodes who received axillary lymph node dissection had more side effects but no improvement in disease-free survival compared with women who had no further lymph node surgery.

Original post: Women with Breast Cancer Micrometastases in Their Sentinel Lymph Nodes May Not Need Axillary Dissection

Potentially Less Toxic Adjuvant Chemotherapy for Women with Breast Cancer

Sat, 13 Apr 2013 16:37:07 +0000

In this phase III trial, women with resected HER2-negative breast cancer that has either spread to nearby lymph nodes or has characteristics associated with a high risk of recurrence will be randomly assigned to receive one of four anthracycline-based chemotherapy regimens or six courses of docetaxel and cyclophosphamide.

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Electrocautery Superior to Topical Treatments for Precancerous Anal Lesions

Fri, 05 Apr 2013 16:37:26 +0000

Results from a randomized clinical trial conducted in Amsterdam suggest that electrocautery is better than topical imiquimod or fluorouracil at treating potentially precancerous anal lesions in HIV-positive men who have sex with men.

Original post: Electrocautery Superior to Topical Treatments for Precancerous Anal Lesions

New Combination Therapy for Untreated Multiple Myeloma

Thu, 28 Feb 2013 17:37:50 +0000

In this phase II trial, people with newly diagnosed multiple myeloma will be treated with carfilzomib, lenalidomide, and dexamethasone for eight 28-day treatment cycles.

Here is the original post: New Combination Therapy for Untreated Multiple Myeloma

Refining Post-Surgical Therapy for Women with Lymph Node-Positive Breast Cancer

Thu, 07 Feb 2013 11:40:04 +0000

In this phase III trial, women with HER2-negative, HR-positive breast cancer and 1-3 positive lymph nodes with recurrence scores of 25 or lower will be randomly assigned either to undergo adjuvant chemotherapy before starting endocrine therapy or to begin endocrine therapy without chemotherapy.

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Refining Post-Surgical Therapy for Women with Lymph Node-Positive Breast Cancer

Thu, 07 Feb 2013 11:40:04 +0000

Original post: Refining Post-Surgical Therapy for Women with Lymph Node-Positive Breast Cancer

New Drug Shows Promise against Drug-Resistant Leukemias

Tue, 18 Dec 2012 17:36:19 +0000

A new drug called ponatinib may be a new treatment option for patients with chronic myeloid leukemia (CML) that is resistant to other therapies, according to results of two early clinical trials.

Treating Patients with High-Risk Smoldering Myeloma

Thu, 13 Dec 2012 17:37:54 +0000

In this phase III clinical trial, patients with smoldering myeloma classified as high risk for progression will be randomly assigned to undergo standard observation or six 4-week courses of treatment with the drug lenalidomide.

Follow this link: Treating Patients with High-Risk Smoldering Myeloma

Treating Patients with High-Risk Smoldering Myeloma

Thu, 13 Dec 2012 17:37:54 +0000

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