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Archive for June 12th, 2012


A Randomized, Phase 2, Neoadjuvant Study of Weekly Paclitaxel With LCL161 in Patients With Triple Negative Breast Cancer

Condition :   Breast Cancer Interventions :   Drug: Paclitaxel + LCL161;   Drug: paclitaxel Sponsors :   Novartis;   Novartis Pharmaceuticals Not yet recruiting – verified June 2012

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Autologous Stem Cell Transplantation and Maintenance Therapy for Multiple Myeloma

Condition :   Multiple Myeloma Interventions :   Drug: Melphalan;   Drug: Lenalidomide Sponsors :   University of Virginia;   University of Virginia Recruiting – verified June 2012

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Assessing the Long Term Effectiveness and Safety of Biotherapies in the Treatment of Psoriasis

Condition :   Psoriasis Intervention :   Sponsors :   Assistance Publique - Hôpitaux de Paris;   Assistance Publique - Hôpitaux de Paris;   French Health Products Safety Agency;   Société Française de Dermatologie;   Janssen, LP;   Pfizer;   Abbott;   Merck Not yet recruiting – verified June 2012

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Comparison Between Remifentanil Target-controlled Infusion and Dexmedetomidine Bolus Administration for Smooth Emergence From General Sevoflurane Anesthesia

Condition :   Thyroid Neoplasm Interventions :   Drug: dexmedetomidine;   Drug: Normal Saline Sponsors :   Yonsei University;   Yonsei University Completed – verified June 2012

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Azacitidine Versus Azacitidine in Combination With Vorinostat in Patients With Relapsed Acute Myeloid Leukaemia

Condition :   Leukemia, Myeloid, Acute Interventions :   Drug: Azacitidine;   Drug: Vorinostat Sponsors :   University of Birmingham;   University of Birmingham;   Leukemia Research Fund;   Celgene Corporation;   Merck Not yet recruiting – verified June 2012

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I-Scan Versus High-definition White Light

Condition :   Colorectal Cancer Interventions :   Device: I-Scan 1;   Device: HD Colon;   Device: I-Scan 2 Sponsors :   University of Calgary;   University of Calgary Recruiting – verified June 2012

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Brentuximab Vedotin in Treating Patients With Steroid-Resistant Acute Graft-Versus-Host Disease

Condition :   Graft Versus Host Disease Interventions :   Drug: brentuximab vedotin;   Other: laboratory biomarker analysis;   Other: pharmacological study Sponsors :   Fred Hutchinson Cancer Research Center;   Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium;   National Cancer Institute (NCI) Not yet recruiting – verified June 2012

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Register With Patients in Which Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) Was Performed

Conditions :   Peritoneal Carcinomatosis;   Pseudomyxoma Peritonei;   Peritoneal Mesothelioma Intervention :   Sponsors :   Universitaire Ziekenhuizen Leuven;   Universitaire Ziekenhuizen Leuven Recruiting – verified March 2012

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Phase II Study of GTx-024 in Women With Metastatic Breast Cancer

Condition :   Metastatic Breast Cancer Interventions :   Drug: GTx-024 3mg;   Drug: GTx-024 9mg Sponsors :   GTx;   GTx Not yet recruiting – verified June 2012

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Pasireotide Therapy in Patients With Nelson’s Syndrome

Condition :   Nelson Syndrome Intervention :   Drug: Pasireotide Sponsors :   Sheffield Teaching Hospitals NHS Foundation Trust;   Sheffield Teaching Hospitals NHS Foundation Trust;   Novartis;   Christie Hospital NHS Foundation Trust;   Oxford University Hospitals NHS Trust;   Barts & The London NHS Trust Recruiting – verified June 2012

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