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Archive for May 17th, 2012


The Genetic Investigation of Reproductive Disorders

Conditions :   Kallmann Syndrome;   Hypogonadotropic Hypogonadism;   Hypothalamic Amenorrhea;   Polycystic Ovarian Syndrome;   Precocious Puberty Intervention :   Sponsors :   Centre Hospitalier Universitaire Vaudois;   Centre Hospitalier Universitaire Vaudois;   Swiss National Science Foundation Recruiting – verified May 2012

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The Association of Ferrtin and Homocysteine Etc. With RI and MS in Polycystic Ovary Syndrome (PCOS)

Condition :   Polycystic Ovary Syndrome Intervention :   Sponsors :   Taipei Medical University WanFang Hospital;   Taipei Medical University WanFang Hospital Recruiting – verified May 2012

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Oxidative Stress and Bisphenol A (BPA) Impact With Polycystic Ovary Syndrome (PCOS)

Conditions :   Oxidative Stress;   Endocrine-Disrupting Chemicals;   Polycystic Ovary Syndrome Intervention :   Sponsors :   Taipei Medical University WanFang Hospital;   Ming-I Hsu Recruiting – verified May 2012

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Mitochondrial Function of Immune Cells in Sepsis

Condition :   Shock, Septic Interventions :   Other: blood sampling;   Other: blood sampling Sponsors :   University Hospital Inselspital, Berne;   University Hospital Inselspital, Berne Not yet recruiting – verified May 2012

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Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Patients With Medulloblastomas With an Activation of the Sonic Hedgehog Pathway

Conditions :   Histologically Confirmed Medulloblastoma;   Activation of the Sonic Hedgehog (SHH) Pathway Interventions :   Drug: vismodegib;   Drug: Temozolomide Sponsors :   Centre Leon Berard;   Centre Leon Berard;   Ministry of Health, France Not yet recruiting – verified May 2012

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Pazopanib and Weekly Topotecan in Patients Recurrent Ovarian Cancer (TOPAZ)

Condition :   Ovarian Cancer Intervention :   Drug: pazopanib in combination with weekly topotecan Sponsors :   Charite University, Berlin, Germany;   JSehouli;   GlaxoSmithKline Not yet recruiting – verified May 2012

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Exact CRC Screening Test: Stool Sample Collection Study to Support Assay Validation Testing

Conditions :   Colorectal Neoplasms;   Digestive System Diseases;   Colonic Diseases;   Colorectal Cancer Intervention :   Sponsors :   Exact Sciences Corporation;   Exact Sciences Corporation Recruiting – verified May 2012

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Effect of Oral Supplementation With a Fibre Enriched Paediatric Sip Feed For Children With Acute Lymphocytic Leukemia

Condition :   Acute Lymphocytic Leukemia Intervention :   Dietary Supplement: NutriniDrink/Fortini MF unflavoured (1.5kcal/ml) Sponsors :   Children’s Cancer Hospital Egypt 57357;   Children’s Cancer Hospital Egypt 57357 Recruiting – verified May 2012

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Experimental Antibody for Treatment-Resistant Liver Cancer

In this trial, patients with unresectable hepatocellular carcinoma who are ineligible for liver transplants or other localized therapies, and who did not benefit from or could not tolerate treatment with sorafenib, will be treated with intravenous TRC105 every 2 weeks.

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High doses of certain dietary supplements increase cancer risk

Beta-carotene, selenium and folic acid — taken up to three times their recommended daily allowance, these supplements are probably harmless. But taken at much higher levels as some supplement manufacturers suggest, these three supplements have now been shown to increase the risk of developing a host of cancers.

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