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Archive for May 14th, 2012


Elderly Metastatic Breast Cancer: Pertuzumab-Herceptin vs Pertuzumab-Herceptin-Metronomic Chemotherapy, Followed by T-DM1

Condition :   Elderly Metastatic Breast Cancer Population Interventions :   Drug: Pertuzumab + trastuzumab;   Drug: Pertuzumab + trastuzumab + metronomic chemotherapy Sponsors :   European Organization for Research and Treatment of Cancer – EORTC;   European Organization for Research and Treatment of Cancer – EORTC Not yet recruiting – verified May 2012

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Double Cord vs. Haploidentical (BMT CTN #1101)

Conditions :   Acute Lymphocytic Leukemia;   Acute Myelogenous Leukemia;   Burkitt’s Lymphoma;   Follicular Lymphoma;   Hodgkin Lymphoma;   Mantle Cell Lymphoma Interventions :   Drug: Biological/Vaccine: Haploidentical BMT;   Drug: Double Cord Blood Transplantation Sponsors :   National Heart, Lung, and Blood Institute (NHLBI);   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI);   Blood and Marrow Transplant Clinical Trials Network Not yet recruiting – verified May 2012

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Dabrafenib Plus Trametinib vs Vemurafenib Alone in Unresectable or Metastatic BRAF V600E/K Cutaneous Melanoma

Condition :   Melanoma Interventions :   Drug: Dabrafenib;   Drug: Vemurafenib;   Drug: Trametinib Sponsors :   GlaxoSmithKline;   GlaxoSmithKline Not yet recruiting – verified May 2012

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Safety And Efficacy Of Crizotinib (Regulatory Post Marketing Commitment Plan)

Condition :   Non-small Cell Lung Cancer Intervention :   Drug: Crizotinib (Xalkori) Sponsors :   Pfizer;   Pfizer Active, not recruiting – verified May 2012

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Bathing Bundle Regimen in Reducing Gynecological Surgical Site Infection in Patients Undergoing Surgery

Condition :   Female Reproductive Cancer Intervention :   Procedure: infection prophylaxis and management Sponsors :   Roswell Park Cancer Institute;   Roswell Park Cancer Institute;   National Cancer Institute (NCI) Recruiting – verified May 2012

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Oral Therapies in Oncology: Cognitive Function and Compliance

Conditions :   Oral Therapies;   Cancer;   Cognitive Function;   Compliance Intervention :   Sponsors :   Centre Francois Baclesse;   Centre Francois Baclesse Recruiting – verified February 2012

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A DB Randomized Study of R1-R2 WaterJel / AloeVera Gel in Prevention of Radiation Dermatitis in Breast Cancer

Conditions :   Breast Cancer;   Radiation Dermatitis;   Erythema Intervention :   Sponsors :   Water-Jel;   Water-Jel Not yet recruiting – verified May 2012

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New Twist On Ancient Math Problem Could Improve Medicine, Microelectronics

A hidden facet of a math problem that goes back to Sanskrit scrolls has just been exposed by nanotechnology researchers at the University of Michigan and the University of Connecticut…

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A Role For DNA Replication Protein In Mitosis, Cancer

The foundation of biological inheritance is DNA replication – a tightly coordinated process in which DNA is simultaneously copied at hundreds of thousands of different sites across the genome. If that copying mechanism doesn’t work as it should, the result could be cells with missing or extra genetic material, a hallmark of the genomic instability seen in most birth defects and cancers…

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Novel Approach To Stimulate Immune Cells Has Potential For Treatment Of Immune Diseases And Cancer

Researchers at Rutgers University have uncovered a new way to stimulate activity of immune cell opiate receptors, leading to efficient tumor cell clearance…

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