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Archive for April 18th, 2012


Norwegian Study Estimates Overdiagnosis of Breast Cancer from Screening

As many as 1 in 4 invasive breast cancers diagnosed in Norway through the country’s widespread, population-based mammography screening program never would have caused the woman harm or required treatment, researchers reported in the April 3 Annals of Internal Medicine.

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NCI Cancer Bulletin for April 17, 2012

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More Chemotherapy May Help after Initial Treatment for Childhood Leukemia Fails

A small percentage of children diagnosed with acute lymphoblastic leukemia (ALL) responds poorly to initial chemotherapy. When this initial treatment, called induction therapy, fails to induce a complete clinical remission, most leukemia experts would recommend an allogeneic stem cell transplant. However, a new study suggests that at least some of these children may do better if they receive additional chemotherapy rather than a stem cell transplant.

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Warren Buffett Says He Has Early Prostate Cancer

Warren Buffett told his company’s shareholders in an open letter Tuesday that he has been diagnosed with early-stage prostate cancer. The 81-year-old billionaire investor says his condition is ‘not remotely life-threatening’ or debilitating. (April 17)

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Long-term Observational Study in HIV Subjects Exposed to EGRIFTA®

Condition :   HIV Intervention :   Drug: Tesamorelin for injection Sponsors :   EMD Serono;   EMD Serono Not yet recruiting – verified April 2012

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Extending Molecular Responses With Nilotinib in Newly Diagnosed Chronic Myeloid Leukemia (CML) Patients in Chronic Phase

Condition :   Extending Molecular Responses With Nilotinib in Newly Diagnosed Chronic Myeloid Leukemia Intervention :   Drug: nilotinib Sponsors :   King Faisal Specialist Hospital & Research Center;   King Faisal Specialist Hospital & Research Center Recruiting – verified April 2012

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Comparison of Prophylactic Antiviral Efficacy in Patients Undergoing Chemotherapy: Entecavir Versus Lamivudine

Conditions :   Malignancy;   Hepatitis B Interventions :   Drug: Entecavir;   Drug: Lamivudine Sponsors :   Seoul National University Hospital;   Seoul National University Hospital Not yet recruiting – verified April 2012

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Genius Study Study to Compare Efficacy and Safety of Gefitinib/ Pemetrexed With Pemetrexed Alone as Maintenance Therapy in Patients With Stage IV EGFR Mutation Negative or T790M Single Mutation Who Respond to Pemetrexed/ Platinum as First-line…

Condition :   NSCLC Interventions :   Drug: Pemetrexed 500mg/m2 iv;   Drug: Pemetrexed 500mg/m2 iv and Gefitinib 250 mg Sponsors :   Taipei Veterans General Hospital,Taiwan;   Taipei Veterans General Hospital,Taiwan;   National Taiwan University Hospital;   Taichung Veterans General Hospital;   China Medical University Hospital;   Dalin Tzu Chi General Hospital Recruiting – verified April 2012

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VSL#3 Versus Placebo in Increasing the Pathological Major Response Rate in Patients With Rectal Cancer

Condition :   Rectal Cancer Interventions :   Other: VSL#3;   Other: Placebo Sponsors :   Catholic University of the Sacred Heart;   Catholic University of the Sacred Heart Recruiting – verified April 2012

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Assess the Efficacy of AZD8931 in Combination With Paclitaxel Versus Paclitaxel Alone in Patients With Gastric Cancer

Condition :   Metastatic, Gastric or Gastro-oesophageal Junction, Cancer Interventions :   Drug: AZD8931;   Drug: Placebo Sponsors :   AstraZeneca;   AstraZeneca Not yet recruiting – verified April 2012

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