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Archive for March 26th, 2012

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A Phase I/II, Open-label Study of Ofatumumab Added to Chlorambucil in Previously Untreated Japanese Patients With Chronic Lymphocytic Leukemia

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Condition :   Leukaemia, Lymphocytic, Chronic Interventions :   Drug: chlorambucil, tablets;   Drug: ofatumumab (GSK1841157) infusion Sponsor :   GlaxoSmithKline Not yet recruiting – verified March 2012

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PHASE Ib/II STUDY OF THE EFFICACY AND SAFETY OF THE R-CMC544/R-GEMOX COMBINATION IN DIFFUSE LARGE B-CELL LYMPHOMA AT FIRST OR SECOND RELAPSE

By on Monday, March 26th, 2012 | No Comments

Condition :   Diffuse Large B-Cell Lymphoma Intervention :   Drug: Rituximab, CMC544, Gemcitabine and Oxaliplatine Sponsors :   Groupe d’Etude des Lymphomes de l’Adulte – Recherche Clinique;   Pfizer Not yet recruiting – verified March 2012

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Ruxolitinib in Patients With Breast Cancer

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Condition :   Breast Cancer Intervention :   Drug: Ruxolitinib Sponsor :   Dana-Farber Cancer Institute Not yet recruiting – verified March 2012

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Safety and Efficacy of Activated Recombinant Human Factor VII in Cirrhotic Patients Undergoing Partial Hepatectomy

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Conditions :   Haemostasis;   Chronic Liver Disease Interventions :   Drug: activated recombinant human factor VII;   Drug: activated recombinant human factor VII;   Drug: placebo Sponsor :   Novo Nordisk Completed – verified March 2012

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Evaluation of Psycho-oncological Intervention in Prostate Cancer Patients on Androgen-deprivation Therapy and Their Partners

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Condition :   Prostate Cancer Intervention :   Other: Psychological counseling Sponsor :   Ipsen Not yet recruiting – verified March 2012

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A Study of MEK162 and AMG 479 in Patients With Selected Solid Tumors

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Conditions :   KRAS Mutated Colorectal Adenocarcinoma.;   Metastatic Pancreatic Adenocarcinoma;   BRAF Mutated Melanoma Intervention :   Drug: MEK 162 + AMG 479 Sponsor :   Novartis Pharmaceuticals Not yet recruiting – verified March 2012

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Clinical Evaluation Of Needle-based Confocal Laser Endomicroscopy in The Lymph Nodes Along With Masses and Cystic Tumors of the Pancreas

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Conditions :   Pancreatic Cyst;   Pancreatic Neoplasms;   Pancreatic Adenoma;   Pancreatic Cancer;   Pancreatic Islet Cell Tumors;   Lymph Node;   Lymphadenopathy Interventions :   Procedure: EUS-FNA;   Procedure: nCLE Sponsor :   Mauna Kea Technologies Not yet recruiting – verified March 2012

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Phase I/II Study of APS001F With Flucytosine and Maltose in Solid Tumors

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Conditions :   Tumors;   Neoplasms;   Cancer Interventions :   Drug: APS001F;   Drug: Flucytosine (5-FC);   Drug: 10% maltose Sponsor :   Anaeropharma Science, Inc. Not yet recruiting – verified March 2012

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Scientists identify novel pathway for T-cell activation in leprosy

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Scientists have pinpointed a new mechanism that potently activates T-cells to fight leprosy. Specifically, the team studied how immune cells located at the site of infection, called dendritic cells, become more specialized to fight leprosy. Dendritic cells deliver key information about an invading pathogen that helps activate the T-cells in launching a more effective attack. The finding may have applications in combating other infectious diseases and cancer.

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One in 10 diagnosed with bowel cancer are dead within a month

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More than half of those are aged over 80 and 60% are only diagnosed when they are admitted to hospital in an emergency More than half of those are aged over 80 and 60% are only diagnosed when they are admitted to hospital in an emergency.

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